{"id":476871,"date":"2023-08-09T09:04:34","date_gmt":"2023-08-09T09:04:34","guid":{"rendered":""},"modified":"2023-09-05T11:13:36","modified_gmt":"2023-09-05T11:13:36","slug":"dna-sequence","status":"publish","type":"wiki","link":"https:\/\/oneproxy.pro\/vn\/wiki\/dna-sequence\/","title":{"rendered":"tr\u00ecnh t\u1ef1 ADN"},"content":{"rendered":"

Tr\u00ecnh t\u1ef1 DNA \u0111\u1ec1 c\u1eadp \u0111\u1ebfn qu\u00e1 tr\u00ecnh x\u00e1c \u0111\u1ecbnh th\u1ee9 t\u1ef1 ch\u00ednh x\u00e1c c\u1ee7a c\u00e1c nucleotide trong ph\u00e2n t\u1eed DNA. N\u00f3 li\u00ean quan \u0111\u1ebfn vi\u1ec7c x\u00e1c \u0111\u1ecbnh th\u1ee9 t\u1ef1 c\u1ee7a b\u1ed1n baz\u01a1\u2014adenine, guanine, cytosine v\u00e0 thymine\u2014t\u1ea1o th\u00e0nh c\u00e1c b\u1eadc trong c\u1ea5u tr\u00fac chu\u1ed7i xo\u1eafn k\u00e9p c\u1ee7a DNA.<\/p>\n

Ngu\u1ed3n g\u1ed1c c\u1ee7a tr\u00ecnh t\u1ef1 DNA<\/h2>\n

N\u1ec1n t\u1ea3ng c\u1ee7a gi\u1ea3i tr\u00ecnh t\u1ef1 DNA \u0111\u01b0\u1ee3c \u0111\u1eb7t ra v\u00e0o \u0111\u1ea7u th\u1ebf k\u1ef7 20 v\u1edbi s\u1ef1 l\u00e0m s\u00e1ng t\u1ecf c\u1ea5u tr\u00fac ph\u00e2n t\u1eed c\u1ee7a DNA b\u1edfi James Watson v\u00e0 Francis Crick v\u00e0o n\u0103m 1953. Tuy nhi\u00ean, b\u1ea3n th\u00e2n k\u1ef9 thu\u1eadt gi\u1ea3i tr\u00ecnh t\u1ef1 n\u00e0y kh\u00f4ng \u0111\u01b0\u1ee3c ph\u00e1t tri\u1ec3n cho \u0111\u1ebfn cu\u1ed1i nh\u1eefng n\u0103m 1970. Hai ph\u01b0\u01a1ng ph\u00e1p ch\u00ednh \u2013 gi\u1ea3i tr\u00ecnh t\u1ef1 Sanger do Frederick Sanger v\u00e0 c\u00e1c \u0111\u1ed3ng nghi\u1ec7p ph\u00e1t tri\u1ec3n, v\u00e0 gi\u1ea3i tr\u00ecnh t\u1ef1 Maxam-Gilbert do Allan Maxam v\u00e0 Walter Gilbert ph\u00e1t tri\u1ec3n \u2013 \u0111\u00e3 d\u1eabn \u0111\u1ea7u cu\u1ed9c c\u00e1ch m\u1ea1ng ban \u0111\u1ea7u trong l\u0129nh v\u1ef1c n\u00e0y. C\u1ea3 hai ph\u01b0\u01a1ng ph\u00e1p \u0111\u1ec1u \u0111\u01b0\u1ee3c c\u00f4ng b\u1ed1 l\u1ea7n \u0111\u1ea7u ti\u00ean v\u00e0o n\u0103m 1977 v\u00e0 v\u00ec nh\u1eefng \u0111\u00f3ng g\u00f3p c\u1ee7a m\u00ecnh, Sanger v\u00e0 Gilbert \u0111\u00e3 chia nhau gi\u1ea3i Nobel H\u00f3a h\u1ecdc n\u0103m 1980.<\/p>\n

L\u00e0m s\u00e1ng t\u1ecf tr\u00ecnh t\u1ef1 DNA<\/h2>\n

Tr\u00ecnh t\u1ef1 DNA r\u1ea5t quan tr\u1ecdng \u0111\u1ec3 hi\u1ec3u \u0111\u01b0\u1ee3c c\u1ea5u tr\u00fac di truy\u1ec1n c\u1ee7a sinh v\u1eadt. N\u00f3 cho ph\u00e9p c\u00e1c nh\u00e0 khoa h\u1ecdc nghi\u00ean c\u1ee9u c\u00e1ch c\u00e1c gen t\u01b0\u01a1ng t\u00e1c v\u1edbi nhau v\u00e0 c\u00e1ch ch\u00fang \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn c\u00e1c \u0111\u1eb7c \u0111i\u1ec3m c\u1ee7a sinh v\u1eadt. Tr\u00ecnh t\u1ef1 DNA bao g\u1ed3m m\u1ed9t chu\u1ed7i ph\u1ea3n \u1ee9ng \u0111\u1ec3 sao ch\u00e9p \u0111o\u1ea1n DNA quan t\u00e2m v\u00e0 x\u00e1c \u0111\u1ecbnh th\u1ee9 t\u1ef1 c\u00e1c nucleotide.<\/p>\n

V\u1ec1 b\u1ea3n ch\u1ea5t, gi\u1ea3i tr\u00ecnh t\u1ef1 DNA d\u1ef1a tr\u00ean c\u00e1c nguy\u00ean t\u1eafc gh\u00e9p c\u1eb7p baz\u01a1 b\u1ed5 sung (adenine v\u1edbi thymine v\u00e0 cytosine v\u1edbi guanine), sao ch\u00e9p DNA v\u00e0 c\u00e1c ph\u01b0\u01a1ng ph\u00e1p ph\u00e1t hi\u1ec7n (th\u01b0\u1eddng l\u00e0 c\u00e1c \u0111\u1ea7u cu\u1ed1i \u0111\u01b0\u1ee3c d\u00e1n nh\u00e3n hu\u1ef3nh quang) \u0111\u1ec3 x\u00e1c \u0111\u1ecbnh th\u1ee9 t\u1ef1 c\u1ee7a c\u00e1c nucleotide.<\/p>\n

C\u1ea5u tr\u00fac b\u00ean trong v\u00e0 ho\u1ea1t \u0111\u1ed9ng c\u1ee7a tr\u00ecnh t\u1ef1 DNA<\/h2>\n

Tr\u00ecnh t\u1ef1 DNA l\u00e0 m\u1ed9t chu\u1ed7i c\u00e1c nucleotide, m\u1ed7i chu\u1ed7i bao g\u1ed3m m\u1ed9t \u0111\u01b0\u1eddng, m\u1ed9t photphat v\u00e0 m\u1ed9t trong b\u1ed1n baz\u01a1. Tr\u00ecnh t\u1ef1 n\u00e0y \u0111\u01b0\u1ee3c \u0111\u1ecdc t\u1eeb \u0111\u1ea7u 5\u2019 \u0111\u1ebfn \u0111\u1ea7u 3\u2019, t\u01b0\u01a1ng \u1ee9ng v\u1edbi chi\u1ec1u d\u00e0i c\u1ee7a s\u1ee3i DNA trong qu\u00e1 tr\u00ecnh sao ch\u00e9p.<\/p>\n

Ho\u1ea1t \u0111\u1ed9ng c\u1ee7a tr\u00ecnh t\u1ef1 DNA ph\u1ee5 thu\u1ed9c v\u00e0o s\u1ef1 k\u1ebft th\u00fac kh\u00e1c bi\u1ec7t c\u1ee7a qu\u00e1 tr\u00ecnh sao ch\u00e9p. V\u00ed d\u1ee5, trong gi\u1ea3i tr\u00ecnh t\u1ef1 Sanger, quy tr\u00ecnh n\u00e0y k\u1ebft h\u1ee3p c\u00e1c dideoxynucleotide k\u1ebft th\u00fac chu\u1ed7i \u0111\u1ec3 ng\u0103n ch\u1eb7n s\u1ef1 k\u00e9o d\u00e0i c\u1ee7a chu\u1ed7i DNA, cho ph\u00e9p x\u00e1c \u0111\u1ecbnh nucleotide cu\u1ed1i c\u00f9ng.<\/p>\n

C\u00e1c t\u00ednh n\u0103ng ch\u00ednh c\u1ee7a tr\u00ecnh t\u1ef1 DNA<\/h2>\n
    \n
  1. \u0110\u1ed9 ch\u00ednh x\u00e1c<\/strong>: Gi\u1ea3i tr\u00ecnh t\u1ef1 DNA mang l\u1ea1i \u0111\u1ed9 ch\u00ednh x\u00e1c cao trong vi\u1ec7c x\u00e1c \u0111\u1ecbnh th\u1ee9 t\u1ef1 c\u00e1c nucleotide trong ph\u00e2n t\u1eed DNA.<\/li>\n
  2. To\u00e0n di\u1ec7n<\/strong>: N\u00f3 cho ph\u00e9p m\u00f4 t\u1ea3 \u0111\u1eb7c \u0111i\u1ec3m c\u1ee7a t\u1ea5t c\u1ea3 c\u00e1c lo\u1ea1i tr\u00ecnh t\u1ef1 DNA, bao g\u1ed3m c\u1ea3 v\u00f9ng m\u00e3 h\u00f3a v\u00e0 kh\u00f4ng m\u00e3 h\u00f3a.<\/li>\n
  3. Kh\u1ea3 n\u0103ng m\u1edf r\u1ed9ng<\/strong>: V\u1edbi nh\u1eefng ti\u1ebfn b\u1ed9 trong c\u00f4ng ngh\u1ec7 nh\u01b0 Gi\u1ea3i tr\u00ecnh t\u1ef1 th\u1ebf h\u1ec7 ti\u1ebfp theo (NGS), gi\u1edd \u0111\u00e2y c\u00f3 th\u1ec3 gi\u1ea3i tr\u00ecnh t\u1ef1 to\u00e0n b\u1ed9 b\u1ed9 gen m\u1ed9t c\u00e1ch hi\u1ec7u qu\u1ea3.<\/li>\n
  4. T\u00ednh thi\u1ebft th\u1ef1c<\/strong>: N\u00f3 cung c\u1ea5p nh\u1eefng hi\u1ec3u bi\u1ebft quan tr\u1ecdng v\u1ec1 c\u00e1c b\u1ec7nh di truy\u1ec1n, m\u1ed1i quan h\u1ec7 ti\u1ebfn h\u00f3a, \u0111a d\u1ea1ng di truy\u1ec1n, v.v.<\/li>\n<\/ol>\n

    C\u00e1c lo\u1ea1i tr\u00ecnh t\u1ef1 DNA<\/h2>\n

    C\u00f3 m\u1ed9t s\u1ed1 lo\u1ea1i ph\u01b0\u01a1ng ph\u00e1p gi\u1ea3i tr\u00ecnh t\u1ef1 DNA. D\u01b0\u1edbi \u0111\u00e2y l\u00e0 m\u1ed9t v\u00e0i c\u00e1i ch\u00ednh:<\/p>\n\n\n\n\n\n\n\n\n
    Ki\u1ec3u<\/th>\nS\u1ef1 mi\u00eau t\u1ea3<\/th>\n<\/tr>\n<\/thead>\n
    Tr\u00ecnh t\u1ef1 sanger<\/td>\nPh\u01b0\u01a1ng ph\u00e1p \u201cch\u1ea5m d\u1ee9t chu\u1ed7i\u201d s\u1eed d\u1ee5ng c\u00e1c phi\u00ean b\u1ea3n \u0111\u1eb7c bi\u1ec7t c\u1ee7a b\u1ed1n nucleotide \u0111\u1ec3 ch\u1ea5m d\u1ee9t qu\u00e1 tr\u00ecnh sao ch\u00e9p DNA \u1edf m\u1ed7i c\u01a1 s\u1edf.<\/td>\n<\/tr>\n
    Tr\u00ecnh t\u1ef1 Maxam-Gilbert<\/td>\nPh\u01b0\u01a1ng ph\u00e1p \u201cph\u00e2n t\u00e1ch b\u1eb1ng h\u00f3a h\u1ecdc\u201d bao g\u1ed3m vi\u1ec7c bi\u1ebfn \u0111\u1ed5i h\u00f3a h\u1ecdc DNA v\u00e0 ph\u00e2n t\u00e1ch ti\u1ebfp theo \u1edf c\u00e1c baz\u01a1 c\u1ee5 th\u1ec3.<\/td>\n<\/tr>\n
    Tr\u00ecnh t\u1ef1 th\u1ebf h\u1ec7 ti\u1ebfp theo (NGS)<\/td>\nC\u00f4ng ngh\u1ec7 th\u00f4ng l\u01b0\u1ee3ng cao cho ph\u00e9p s\u1eafp x\u1ebfp h\u00e0ng tri\u1ec7u m\u1ea3nh c\u00f9ng m\u1ed9t l\u00fac.<\/td>\n<\/tr>\n
    Tr\u00ecnh t\u1ef1 th\u1ebf h\u1ec7 th\u1ee9 ba<\/td>\nM\u1ed9t c\u00f4ng ngh\u1ec7 \u0111\u1ecdc c\u00e1c ph\u00e2n t\u1eed DNA ri\u00eang l\u1ebb, cho ph\u00e9p th\u1eddi gian \u0111\u1ecdc d\u00e0i h\u01a1n v\u00e0 kh\u1ea3 n\u0103ng gi\u1ea3i tr\u00ecnh t\u1ef1 theo th\u1eddi gian th\u1ef1c.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

    \u1ee8ng d\u1ee5ng, v\u1ea5n \u0111\u1ec1 v\u00e0 gi\u1ea3i ph\u00e1p gi\u1ea3i tr\u00ecnh t\u1ef1 DNA<\/h2>\n

    Tr\u00ecnh t\u1ef1 DNA c\u00f3 nhi\u1ec1u \u1ee9ng d\u1ee5ng t\u1eeb ch\u1ea9n \u0111o\u00e1n y t\u1ebf \u0111\u1ebfn sinh h\u1ecdc ti\u1ebfn h\u00f3a. Tuy nhi\u00ean, n\u00f3 c\u0169ng ph\u1ea3i \u0111\u1ed1i m\u1eb7t v\u1edbi m\u1ed9t s\u1ed1 th\u00e1ch th\u1ee9c nh\u01b0 l\u1ed7i tr\u00ecnh t\u1ef1, chi ph\u00ed cao v\u00e0 c\u00e1c v\u1ea5n \u0111\u1ec1 v\u1ec1 l\u01b0u tr\u1eef d\u1eef li\u1ec7u. C\u00e1c gi\u1ea3i ph\u00e1p th\u01b0\u1eddng li\u00ean quan \u0111\u1ebfn c\u1ea3i ti\u1ebfn c\u00f4ng ngh\u1ec7 (v\u1ec1 t\u1ef7 l\u1ec7 l\u1ed7i), t\u0103ng kinh ph\u00ed (v\u1ec1 chi ph\u00ed) v\u00e0 c\u00e1c c\u00f4ng c\u1ee5 tin sinh h\u1ecdc ti\u00ean ti\u1ebfn (\u0111\u1ec3 l\u01b0u tr\u1eef v\u00e0 gi\u1ea3i th\u00edch d\u1eef li\u1ec7u).<\/p>\n

    Tr\u00ecnh t\u1ef1 DNA so v\u1edbi c\u00e1c thu\u1eadt ng\u1eef t\u01b0\u01a1ng t\u1ef1<\/h2>\n\n\n\n\n\n\n\n\n
    Thu\u1eadt ng\u1eef<\/th>\nS\u1ef1 mi\u00eau t\u1ea3<\/th>\n<\/tr>\n<\/thead>\n
    X\u00e9t nghi\u1ec7m DNA<\/td>\nQu\u00e1 tr\u00ecnh x\u00e1c \u0111\u1ecbnh th\u1ee9 t\u1ef1 ch\u00ednh x\u00e1c c\u1ee7a c\u00e1c nucleotide trong ph\u00e2n t\u1eed DNA.<\/td>\n<\/tr>\n
    Tr\u00ecnh t\u1ef1 b\u1ed9 gen<\/td>\nM\u1ed9t quy tr\u00ecnh s\u00e2u r\u1ed9ng h\u01a1n bao g\u1ed3m vi\u1ec7c gi\u1ea3i tr\u00ecnh t\u1ef1 to\u00e0n b\u1ed9 DNA c\u1ee7a sinh v\u1eadt.<\/td>\n<\/tr>\n
    Tr\u00ecnh t\u1ef1 Exome<\/td>\nM\u1ed9t k\u1ef9 thu\u1eadt t\u1eadp trung v\u00e0o vi\u1ec7c gi\u1ea3i tr\u00ecnh t\u1ef1 c\u00e1c v\u00f9ng m\u00e3 h\u00f3a protein c\u1ee7a b\u1ed9 gen.<\/td>\n<\/tr>\n
    Ki\u1ec3u gen<\/td>\nM\u1ed9t qu\u00e1 tr\u00ecnh x\u00e1c \u0111\u1ecbnh nh\u1eefng kh\u00e1c bi\u1ec7t trong c\u1ea5u tr\u00fac di truy\u1ec1n b\u1eb1ng c\u00e1ch ki\u1ec3m tra tr\u00ecnh t\u1ef1 DNA t\u1ea1i c\u00e1c v\u1ecb tr\u00ed c\u1ee5 th\u1ec3.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

    Quan \u0111i\u1ec3m v\u00e0 c\u00f4ng ngh\u1ec7 t\u01b0\u01a1ng lai<\/h2>\n

    T\u01b0\u01a1ng lai c\u1ee7a gi\u1ea3i tr\u00ecnh t\u1ef1 DNA n\u1eb1m \u1edf vi\u1ec7c n\u00e2ng cao t\u1ed1c \u0111\u1ed9, \u0111\u1ed9 ch\u00ednh x\u00e1c v\u00e0 kh\u1ea3 n\u0103ng chi tr\u1ea3 c\u1ee7a quy tr\u00ecnh. C\u00e1c k\u1ef9 thu\u1eadt m\u1edbi n\u1ed5i nh\u01b0 gi\u1ea3i tr\u00ecnh t\u1ef1 nanopore v\u00e0 s\u1eed d\u1ee5ng CRISPR \u0111\u1ec3 gi\u1ea3i tr\u00ecnh t\u1ef1 m\u1ee5c ti\u00eau c\u00f3 nhi\u1ec1u h\u1ee9a h\u1eb9n. Ngo\u00e0i ra c\u00f2n c\u00f3 m\u1ed1i quan t\u00e2m ng\u00e0y c\u00e0ng t\u0103ng \u0111\u1ed1i v\u1edbi vi\u1ec7c ph\u00e1t tri\u1ec3n c\u00e1c tr\u00ecnh s\u1eafp x\u1ebfp di \u0111\u1ed9ng cho c\u00e1c \u1ee9ng d\u1ee5ng th\u1eddi gian th\u1ef1c t\u1ea1i ch\u1ed7.<\/p>\n

    M\u00e1y ch\u1ee7 proxy v\u00e0 tr\u00ecnh t\u1ef1 DNA<\/h2>\n

    M\u1eb7c d\u00f9 c\u00e1c m\u00e1y ch\u1ee7 proxy v\u00e0 tr\u00ecnh t\u1ef1 DNA n\u1eb1m \u1edf c\u00e1c l\u0129nh v\u1ef1c kh\u00e1c nhau nh\u01b0ng ch\u00fang h\u1ed9i t\u1ee5 trong l\u0129nh v\u1ef1c qu\u1ea3n l\u00fd d\u1eef li\u1ec7u. Trong gi\u1ea3i tr\u00ecnh t\u1ef1 DNA, m\u1ed9t l\u01b0\u1ee3ng l\u1edbn d\u1eef li\u1ec7u \u0111\u01b0\u1ee3c t\u1ea1o ra. M\u00e1y ch\u1ee7 proxy c\u00f3 th\u1ec3 gi\u00fap qu\u1ea3n l\u00fd d\u1eef li\u1ec7u n\u00e0y b\u1eb1ng c\u00e1ch cung c\u1ea5p quy\u1ec1n truy c\u1eadp an to\u00e0n v\u00e0 hi\u1ec7u qu\u1ea3 v\u00e0o c\u00e1c c\u00f4ng c\u1ee5 v\u00e0 c\u01a1 s\u1edf d\u1eef li\u1ec7u tin sinh h\u1ecdc. H\u1ecd c\u0169ng c\u00f3 th\u1ec3 b\u1ea3o v\u1ec7 qu\u00e1 tr\u00ecnh truy\u1ec1n d\u1eef li\u1ec7u kh\u1ecfi c\u00e1c m\u1ed1i \u0111e d\u1ecda m\u1ea1ng ti\u1ec1m \u1ea9n.<\/p>\n

    Li\u00ean k\u1ebft li\u00ean quan<\/h2>\n
      \n
    1. Vi\u1ec7n nghi\u00ean c\u1ee9u b\u1ed9 gen ng\u01b0\u1eddi qu\u1ed1c gia - Tr\u00ecnh t\u1ef1 DNA<\/a><\/li>\n
    2. Trung t\u00e2m Th\u00f4ng tin C\u00f4ng ngh\u1ec7 Sinh h\u1ecdc Qu\u1ed1c gia<\/a><\/li>\n
    3. Hi\u1ec7p h\u1ed9i sinh h\u1ecdc t\u00ednh to\u00e1n qu\u1ed1c t\u1ebf<\/a><\/li>\n
    4. Vi\u1ec7n Sanger Wellcome<\/a><\/li>\n<\/ol>","protected":false},"featured_media":468240,"menu_order":0,"template":"","meta":{"_acf_changed":false,"content-type":"","inline_featured_image":false,"footnotes":""},"class_list":["post-476871","wiki","type-wiki","status-publish","has-post-thumbnail","hentry"],"acf":{"faq_title":"Frequently Asked Questions about The Fascinating Universe of DNA Sequencing<\/mark>","faq_items":[{"question":"What is DNA sequencing?","answer":"

      DNA sequencing refers to the process of determining the precise order of nucleotides within a DNA molecule. It involves techniques to identify the sequence of the four bases\u2014adenine, guanine, cytosine, and thymine\u2014that make up the DNA molecule.<\/p>"},{"question":"When and how did DNA sequencing originate?","answer":"

      The concept of DNA sequencing originated in the late 1970s. Two key methods\u2014Sanger sequencing developed by Frederick Sanger and colleagues, and Maxam-Gilbert sequencing developed by Allan Maxam and Walter Gilbert\u2014were the pioneers in this field. Both these methods were first published in 1977, earning Sanger and Gilbert the 1980 Nobel Prize in Chemistry.<\/p>"},{"question":"How does DNA sequencing work?","answer":"

      DNA sequencing relies on the principles of complementary base pairing, DNA replication, and detection methods to identify the order of nucleotides. Techniques like Sanger sequencing use chain-terminating dideoxynucleotides that halt the DNA strand extension, allowing the identification of the terminal nucleotide.<\/p>"},{"question":"What are the key features of DNA sequencing?","answer":"

      DNA sequencing is precise, comprehensive, scalable, and offers high utility. It allows for accurate determination of nucleotide order, characterization of all types of DNA sequences, and provides vital insights into genetic diseases, evolutionary relationships, and genetic diversity.<\/p>"},{"question":"What are the different types of DNA sequencing?","answer":"

      Several types of DNA sequencing methods exist including Sanger Sequencing, Maxam-Gilbert Sequencing, Next-Generation Sequencing (NGS), and Third-Generation Sequencing. Each of these methods has distinct characteristics and applications.<\/p>"},{"question":"What are the applications and challenges of DNA sequencing?","answer":"

      DNA sequencing has applications ranging from medical diagnostics to evolutionary biology. It faces challenges like sequencing errors, high costs, and data storage issues. Solutions often involve technological advancements, increased funding, and sophisticated bioinformatics tools.<\/p>"},{"question":"How can proxy servers be used in relation to DNA sequencing?","answer":"

      Proxy servers can be useful in the data management aspect of DNA sequencing, which often involves handling massive amounts of data. Proxy servers provide secure and efficient access to bioinformatics tools and databases and help safeguard data transfer processes from potential cyber threats.<\/p>"},{"question":"What does the future hold for DNA sequencing?","answer":"

      The future of DNA sequencing lies in enhancing its speed, accuracy, and affordability. Emerging techniques such as nanopore sequencing and the use of CRISPR for targeted sequencing hold considerable promise. The development of portable sequencers for on-site, real-time applications is also on the horizon.<\/p>"}]},"_links":{"self":[{"href":"https:\/\/oneproxy.pro\/vn\/wp-json\/wp\/v2\/wiki\/476871","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/oneproxy.pro\/vn\/wp-json\/wp\/v2\/wiki"}],"about":[{"href":"https:\/\/oneproxy.pro\/vn\/wp-json\/wp\/v2\/types\/wiki"}],"version-history":[{"count":0,"href":"https:\/\/oneproxy.pro\/vn\/wp-json\/wp\/v2\/wiki\/476871\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/oneproxy.pro\/vn\/wp-json\/wp\/v2\/media\/468240"}],"wp:attachment":[{"href":"https:\/\/oneproxy.pro\/vn\/wp-json\/wp\/v2\/media?parent=476871"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}